I'm sorry to hear of your wife's diagnosis. Hope this site can offer some support, information, or whatever it is you need. It sounds as though you have a good plan in place for treatment. The one thing that I do know is that Tarceva can be rendered ineffective if grapefruit or grapefruit juice is taken.
4/05 - 8cm x5cm tumor upper left lung. Bone and Brain mets. 6/05 radiation to spine and left clavicle. 7/05 stereotactic brain radiation. 8/05 chemo started, trial of gemcitibine and carboplatin. 9/05 ct indicates some shrinkage. 11/7 ct indicates additional shrinkage.
10/18 brain mri inconclusive, re do in 6 wks; 12/13 brain and spine mri, results are spine is fine, brain uncertain if its progression or necrosis. Brain Pet scan 12/22, results are no sign of cancer. CT 1/3 showed 9% reduction. 2 more cycles ordered.
2/2006 CT shows no change. Removed from trial but kept on the same drugs to allow for a reduction in dosage. Having difficulty with blood counts, so reduced dosage is to try and keep me on schedule. 3/06 Brain MRI shows new met. Treament undetermined as yet.
4/20 switched to Alimta due to bad blood counts on the gemcitabine/carboplatin.
4/20 Brain PET and MRI show necrosis where radiosurgery was used. May require surgery or medication.
6/4/06 - bone scan shows pretty clean can't find cause of flank pain.
6/15/06 - MRI for spine and Brain. Results 6/21 and neither were great. The pain seems to be coming from a tumor around T8 and unfortunately 2 new bain mets.
6/24 - changed from Altima to Taxotera. Scheduled for sim and then 10 days of radiation. Also scheduled for radio surgey.
7/5 - began 10 days radiation
7/13 - radio surgey for brain mets*
7/15 - Taxotere 3xMonth
10/18 - Brain scan no new lesions, treated lesions responding
10/18 - spine MRI, shows two fractures, but not cauing pain or symptoms.
11/1 - Brain MR Spect. Like an MRI, but maybe has some PET scan properties as well. Results consistent with the last MRI.
11/27 - headaches, new MRI, shows new lesions developed in less than 1 month. headache is caused by previously treated lesions where edema has resulted.
12/1 - started Tarceva
1/9 - Onc has me off Tarceva for a week to clear up a nail infection. Then back on it.
1/14 - I will be starting tremador which is a brain tumor chemo. Seeing if there might be a benefit as an alternative to WBR.
1/18 - Brain MRI looks good. All new mets except one seem smaller. Treated mets look good, edema almost gone. Doctors to confer and determine if Radio Surgery on 2 mets (6 total) or just wait and see.