What do I need to know about my diagnosis?

A Stage III lung cancer diagnosis means the disease has progressed locally beyond the primary site into nearby tissues or lymph nodes. Because Stage III is highly diverse and complex, obtaining a precise picture of your specific tumor is essential. This page will guide you through the nuances of Stage III, the diagnostic tests used to evaluate your lungs, and how biomarker testing serves as a vital tool for treatment planning.

What is Stage III NSCLC?

Stage III is often described as “locally advanced” lung cancer. In these videos, we break down the critical distinctions within this stage, including the differences between Stage IIIB and IIIC, and explore the unique clinical complexities that your medical team evaluates when determining the boundaries of the disease.

Please click the boxes below to watch the videos.

What is Stage III lung cancer?
What are the nuances and complexities of Stage III NSCLC?
Click here to watch the American Cancer Society's videos on staging. Click here for more information about lung cancer staging.

Which tests are used to confirm my diagnosis?

To build an effective, personalized map for your care, your team relies on diagnostic staging. The experts in these videos explain the specialized tests used to evaluate your lung health and look closely at lymph nodes, as well as the surgeon's specialized role in clarifying the exact reach of the tumor.

What are pulmonary function tests (PFTs), and why are they important?
What is EBUS, and how does it help with diagnosis?
What is the surgeon's role in cancer staging, and what tools do you use for staging?
Click here for more information about diagnosing lung cancer.

What is biomarker testing, and why is it important?

Biomarker and molecular testing play a vital role in mapping out Stage III care. In these videos, cancer experts discuss how identifying specific cellular mutations helps determine if targeted therapies or clinical trials are options for you, and how pulmonologists work to ensure enough tissue is safely captured for these deep-dive analyses.

Why is biomarker and molecular testing important, and is it done during surgery?
What is the role of biomarkers in Stage III, and when is targeted therapy used? Should patients with other biomarkers consider clinical trials?
What is the pulmonologist's role in ensuring enough tissue is collected for biomarker testing?
Click here to listen to the LUNGevity podcast “What are Biomarkers and Why Should You Get Tested?" Click here for more information about biomarker testing.