Transposon Mutagenesis for Lung Cancer Gene Discovery

Funded equally by LUNGevity Foundation and the Illinois Chapter of the American Cancer Society
Timothy K. Starr, PhD
University of Minnesota Department of Genetics, Cell Biology and Development
Minneapolis

In order to identify mutated genes that cause lung cancer, Dr. Starr has developed a system that is capable of randomly mutating genes within cells, resulting in tumor formation. The genes mutated by this method can easily be identified using standard molecular biology techniques. He can then test their role in lung cancer formation.