Targeting Gamma-Secretase and the Notch Pathway in Lung Cancer

Funded equally by LUNGevity Foundation and American Lung Association National Office
Thao Dang, MD
Vanderbilt University Medical Center
Nashville

Dr. Dang is studying the anti-tumor effect of gamma-secretases inhibitors, compounds that inhibit activation of the Notch pathway that is active in lung cancer cells. She is studying its effect both alone and in combination with traditional chemotherapy and targeted therapy.