Rising Tide logoThe 2024 Rising Tide/LUNGevity Team Award to Target Mechanisms of Resistance is now open for application submissions.

The Rising Tide/LUNGevity Team Award to Target Mechanisms of Resistance will fund high-impact interventional clinical trials that seek to develop therapeutic strategies targeting shared mechanisms of resistance in oncogene-driven lung adenocarcinoma (LUAD). Projects funded are expected to further our knowledge of shared mechanisms of resistance across oncogene-driven LUAD and how they can be targeted using novel pharmaceutical agents (monotherapies or combination therapies). The program has no geographical restrictions and is open to both US and non-US applicants.

Award Guidelines

  • Applicants must hold a doctoral degree and faculty appointment (or equivalent) with an academic institution, including research institutions that are not formally associated with a university, and have completed a postdoctoral training fellowship.
  • Awards may be for a maximum of $1,500,000 ($500,000 per year for 3 years)
  • This is a team award and at least two institutions are required to be involved right from the LOI stage
  • A Patient Engagement Plan will be a required as part of the application
  • Annual milestones must be met

Note: LUNGevity will grant only one award per institution.

LUNGevity uses a two-step application process:

  1. A letter of intent (LOI), with a brief overview of the proposed project and biographical information
  2. A full application with an extended narrative about the project, as well as supporting information and documentation. (Because the number of awards is limited, only a subset of applicants will be invited to submit a full application after the LOI review is completed.)

Reviewers are drawn from LUNGevity’s Scientific Advisory Board and other lung cancer experts. Awardees have progress and financial reporting obligations during their award term.

A complete description of the award, terms and conditions, and instructions are included in the 2024 Rising Tide/LUNGevity Team Award to Target Mechanisms of Resistance RFA. All application materials must be submitted electronically via proposalCENTRAL.

2024 Application Timeline

LOIs due:   by February 16, 2024, 11:59 pm EST
Invitations to apply:   No later than March 25, 2024
Applications due:   May 15, 2024, 11:59 pm EDT
Award announcement:   Late summer 2024
Award start date:   November 1, 2024